Advanced Normalization Tools

Questions: Discussion Site
Email: antsr.me at gmail dot com
Install ANTs via pre-built: Packages
Build ANTs from: Source-Code (recommended)

ANTs extracts information from complex datasets that include imaging (Word Cloud). Paired with ANTsR (answer), ANTs is useful for managing, interpreting and visualizing multidimensional data. ANTs is popularly considered a state-of-the-art medical image registration and segmentation toolkit. ANTsR is an emerging tool supporting standardized multimodality image analysis. ANTs depends on the Insight ToolKit (ITK), a widely used medical image processing library to which ANTs developers contribute.

Authors

Brian B. Avants - UPENN

Role: Creator, Algorithm Design, Implementation, more

Nicholas J. Tustison - UVA

Role: Compeller, Algorithm Design, Implementation Guru

Team: Gang Song (Originator), Jeffrey T. Duda (DTI), Hans J. Johnson (Large-Scale Application, Testing)

Methods References

Image Registration

Diffeomorphisms: SyN, Independent Evaluation: Klein, Murphy, Template Construction (2004) (2010), Similarity Metrics, Multivariate registration, Multiple modality analysis and statistical bias

Image Segmentation

Atropos Multivar-EM Segmentation (link), Multi-atlas methods (link), Bias Correction (link), DiReCT cortical thickness (link), DiReCT in chimpanzees

Multivariate Analysis Eigenanatomy (1) (2)

Prior-Based Eigenanatomy (in prep), Sparse CCA (1), (2), Sparse Regression (link)

ImageMath Useful!

morphology, GetLargestComponent, CCA, FillHoles ... much more!

Application Domains

Frontotemporal degeneration PENN FTD center

Neuroimaging Multimodality

Structural MRI
Functional MRI
Network Analysis

Lung imaging Translational

Structure
Perfusion MRI
Branching

Background & Theory

The SyN and N4 bias correction papers and other relevant references in Pubmed
Visualization: e.g. a gource of ANTs development
DiReCT cortical thickness papers
A folder of relevant docs: segmentation, registration, usage(old), for clinical apps
ANTs redesigned for generality, automation, multi-core computation with ITKv4
Dev'd ITKv4 with Kitware, GE, Natl. Lib of Medicine & Academia

Acclaim for Robustness & Other News

ANTs has won several competitions Unbiased & international

New antsRegistration bash example
New Eigenanatomy for multivariate neuroimage analysis via PCA & CCA
ANTs finished in 1st rank in Klein 2009 intl. brain mapping competition
ANTs finished 1st overall in EMPIRE10 intl. lung mapping competition
ANTs is the standard registration for MICCAI-2013 segmentation competitions
Conducting ANTs-based R tutorial @ MICCAI-2013
ITK-focused Frontiers in Neuroinformatics research topic here

Learning about ANTs

Presentations: e.g. a Prezi about ANTs (WIP)

Reproducible science as a teaching tool: e.g. compilable ANTs tutorial (WIP)